There is a lot of things that help live play. For instance get a foot switch and use it to say change banks sequences tracks or what ever. you can even make one.
I use the sequencer a lot to, and play live in multiple passes on different tracks to build it up. Then listen to it, change it, do it agin, so its like i am always live. What you hear is a compilation of live playing, be it chords or MIDI data say for a synth filter.
Case in point, i was playing with this track today. And its all saved so now i can make more variations and switch it up more or what ever i think i need to do next. I mean THis is totally live
to four track yeah. Made it all my self. no loop packs or anything, just MPC1000 JJOSXL and some synths to 4 track live. meaning its unedited. I can sit back and go with it or change it as it plays with more rolls, mutes, patterns samples ect. I need another footswitch as one is not enough.
The sequence window is good to for switching stuff, just set it up the way you want it to switch before hand of course.

i could rock that beat all day to, just cos its one of my fave styles like.
So yeah i mean you can try and play "everything" but it if you have to layer lots makes sense to make use of the sequencer. Patterns are good to as they stay in time to tempo changes if you use them as opposed to samples that are not chopped. I chop but. as you can hear in my breakbeat there is a chopped drumbreak as well as sequenced break I wrote underneath. There is a whole load of stuff i want to do to it and it might take a while to do it to. Gotta do the whole resample thing, and write more to. maybe more sound design its a rabbit hole, but you get the picture. Live and sequenced and live again and again if you want then you can resample or pattern it.
I liked the vid to.