That depends on the product. Assuming you are talking about the MPC software, I think Akai gives you 2 or 3 activations. You can activate it on as many computers (or dongles) as you have activations. Unless you bought a product that specifically tells you it needs an iLok Dongle or the Cloud Service, it can all be done on your desktop.
I just moved all of mine over to an iLok last month when I got my new M2 Mac, and after moving my activated licenses to USB, I can still use the remaining activations for my computer if I want to. I dont know why but the stupid Softube installer always activates one on your desktop AND your dongle if you have one, at least it does to me every time I update or install something new.