I have the Axiom Pro 49 along with Logic, Pro Tools, Cubase, Reason, etc. The point being that it integrates with all of them as there are presets for each one. Very simple to use to be honest as the stock plug-ins and sounds are set up as well.
Do keep in mind that when using it in software mode you have to hit the edit button, hit button #5 for the midi mode, tab down and make sure it says "USB Panic". If using it as hardware controller do the same thing but change it to "Kyb Panic". Otherwise, you'll be wondering why it's not working.
I've had mine for about 2 years with no problems at all so it's very reliable.