
If you connect the RPM3 to your computer via USB, then they can be set as the USB audio interface, which you would select in MPC Software preferences as your output audio device, and you would not have audio coming out of the Renaissance outputs.
You would probably be better off connecting them via the 1/4" audio inputs, or RCA audio inputs.
I would connect the Renaissance Stereo Out L/R 1/4" outputs to the RPM3 1/4" inputs.
The Renaissance has balanced 1/4" outputs.
I can not find any mention as to whether the RPM3 1/4" inputs are balanced or unbalanced.
If the RPM3 inputs are balanced, it might be best to use a balanced 1/4" TRS to TRS cable to connect them to the Renaissance Stereo Outs, but you can also use unbalanced 1/4" TS to TS cables.
If the RPM3 inputs are unbalanced, just use normal unbalanced 1/4" TS to TS cables to connect them to the Renaissance Stereo Outs.
You have quite a few different audio interface options, the Renaissance built-in audio interface, the EIE Pro, and the RPM3, and you can connect them and use them in different ways, how you do so is really up to you.