yeah, panning can work well if you have 2 frequencies clashing for space, but i usually do a mixture of panning and eq when trying to blend stuff thats clashing. like you said.
ie. i just worked on mixing a song that had 3 parts for the hook that were very similar frequencies, each started at 8khz and peaked in 3 similar spots from there.
i ended up finding where each instrument had the "most" of its sound, and cut each of the other two instruments from there, so in the end, there was still a well defined place for each of the 3 frequencies to sit, it was just one instrument that dominated each space though.
i made sure not to cut out the clashing frequencies in the other instruments all the way though, becasue afterwards i used a bit of panning to have them directed to their own space.
it seems to me that usually a vocal and main sample will be taking up the same space though, (ie both panned in the middle) so i def agree that subtracting a bit of the clashing frequency sounds like a better idea than boosting and still having a clash. im still working on utilizing this to its fullest potential myself though.
good luck with all the tips you have been getting in this thread, im sure youll start getting your overdubs and vocals sounding alot better with some practice!
