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First you need to get all those programs and sequences out of memory. Then go to the save mode, and select internal memory and "save all seq. and programs."
This will save the empty seq. and programs OVER the DEMO seq. and programs.
You can also load your own programs, an d when you "save all seq. and programs" to internal memory THOSE programs will be saved over the demos.
I'm pretty sure you have to have at least one sound in the internal memory though. I've tried clearing it by saving blank programs and sequences, it works for both but says there is no sample to save, so I have to have something in there to overwrite the demo sounds/sequences.